Opaleye Management Inc.

Opaleye Management Inc. latest Q4_2020 13F filings reported $765,570,000 in market value on this 2021-02-12 report date . The portfolio quarterly return is 49.72%. This fund has 59 securities concentrations of 100% weights.

Opaleye Management Inc. largest holding is Ocular Therapeutix Inc. with weight of 17.60% and $134,758,000 in market value. The portfolio return is computed based on the amount invested in the new quarter. The following shows the portfolio details.

Portfolio Performance History

FILE DATEREPORT PERIODQTR YEARFILE TYPENOS. OF STOCKSREPORTED VALUERETURN
2021-02-122020-12-31Q4_202013F-HR59$765,570,00049.72%
2020-11-162020-09-30Q3_202013F-HR55$511,320,0003.27%
2020-08-142020-06-30Q2_202013F-HR48$495,150,00031.23%
2020-05-152020-03-31Q1_202013F-HR43$377,310,000-25.97%
2020-02-142019-12-31Q4_201913F-HR47$509,651,00084.29%
2019-11-142019-09-30Q3_201913F-HR49$276,541,000-15.71%
2019-08-142019-06-30Q2_201913F-HR43$328,094,000-9.15%
2019-05-152019-03-31Q1_201913F-HR53$361,134,00034.76%
2019-02-142018-12-31Q4_201813F-HR47$267,975,000-31.82%
2018-11-142018-09-30Q3_201813F-HR47$393,047,0001.73%
2018-08-142018-06-30Q2_201813F-HR36$386,358,00010.47%
2018-05-142018-03-31Q1_201813F-HR38$349,747,00011.99%
2018-02-092017-12-31Q4_201713F-HR35$312,298,00010.44%
2017-11-142017-09-30Q3_201713F-HR34$282,772,00018.12%
2017-08-142017-06-30Q2_201713F-HR41$239,398,00019.15%
2017-05-152017-03-31Q1_201713F-HR44$200,928,00018.39%
2017-02-212016-12-31Q4_201613F-HR40$169,717,000-11.18%
2016-11-142016-09-30Q3_201613F-HR44$191,082,00027.64%
2016-08-122016-06-30Q2_201613F-HR49$149,709,000-6.64%
2016-08-122016-06-30Q2_201613F-HR/A49$149,709,0000.00%
2016-05-272016-03-31Q1_201613F-HR/A52$160,362,0000.00%

Portfolio Details

Stock NameTickersValueCurrent Value (x1000)Change Value %WeightComputed PriceShares Change %Current Shares
OCULAR THERAPEUTIX INCOCULINCR$134,7581.96%17.60%$20.700.09%6,510,000
PROTARA THERAPEUTICS INCTARAINCR$61,9410.44%8.09%$24.210.00%2,558,472
EIDOS THERAPEUTICS INCBBIOINCR$41,5201.60%5.42%$131.580.00%315,550
ETON PHARMACEUTICALS INCETONINCR$32,8450.14%4.29%$8.130.11%4,040,000
CODEXIS INCCDXSINCR$30,5620.86%3.99%$21.830.00%1,400,000
CARDIFF ONCOLOGY INC COMCRDFINCR$29,9080.22%3.91%$17.99-0.04%1,662,500
TRACON PHARMACEUTICALS INCTCONINCR$29,4651.83%3.85%$11.700.25%2,518,371
CHEMOCENTRYX INCCCXIINCR$21,6720.11%2.83%$61.92-0.02%350,000
ACUTUS MED INCAFIBDECR$21,607-0.03%2.82%$28.810.00%749,990
HARROW HEALTH INCHROWINCR$21,0290.27%2.75%$6.860.04%3,065,416
TG THERAPEUTICS INCTGTXINCR$20,1580.93%2.63%$52.02-0.01%387,500
XOMA CORP DELXOMAINCR$20,0791.34%2.62%$44.130.00%455,000
NEOLEUKIN THERAPEUTICS INCNLTXINCR$19,5470.17%2.55%$14.100.00%1,386,300
CHIMERIX INCCMRXINCR$19,1101.00%2.50%$4.830.03%3,956,500
CELLDEX THERAPEUTICS INC NEWCLDXINCR$17,3800.18%2.27%$17.520.00%992,000
STEREOTAXIS INCSTXSINCR$15,3790.42%2.01%$5.090.00%3,021,436
DECIPHERA PHARMACEUTICALS INDCPHINCR$12,6700.11%1.65%$57.070.00%222,000
FORTRESS BIOTECH INCFBIOINCR$12,3230.20%1.61%$3.170.02%3,887,500
CYTOKINETICS CYTKINCR$12,1111.68%1.58%$20.781.79%582,800
MYOVANT SCIENCES LTDMYOVINCR$10,4870.09%1.37%$15.370.00%682,500
LUMOS PHARMA INCLUMOINCR$10,0452.02%1.31%$35.710.17%281,287
BIOHAVEN PHARMACEUTICAL HOLD USD0.000000BHVNINCR$9,7710.31%1.28%$85.710.00%114,000
SERES THERAPEUTICS INCMCRBINCR$9,8040.03%1.28%$29.240.00%335,312
KALVISTA PHARMACEUTICALS INCKALVINCR$8,9290.52%1.17%$18.990.00%470,203
VAXCYTE INCPCVXDECR$8,906-0.42%1.16%$26.570.07%335,200
MACROGENICS MGNXDECR$8,472-0.36%1.11%$22.86-0.30%370,600
FS DEV CORPGMTXBUY$7,7480.00%1.01%$11.000.00%704,400
PROTAGONIST THERAPEUTICS INCPTGXBUY$7,0200.00%0.92%$27.000.00%260,000
SUTRO BIOPHARMA INCSTROINCR$6,9953.77%0.91%$21.711.21%322,200
CERECOR INCCERCDECR$6,917-0.10%0.90%$2.64-0.22%2,620,000
INFINITY PHARMACEUTICALS INCINFIINCR$6,72448.08%0.88%$2.120.00%3,171,800
TRICIDA INCTCDABUY$6,7610.00%0.88%$7.050.00%959,000
FIVE PRIME THERAPEUTICS INCFPRXBUY$6,4960.00%0.85%$17.010.00%381,900
ADAMAS PHARMACEUTICALS INCADMSINCR$6,4420.05%0.84%$4.330.00%1,487,800
Merus N.V.MRUSINCR$6,1883093.00%0.81%$17.531764.00%353,000
SIO GENE THERAPIES INCSIOXBUY$5,5600.00%0.73%$2.780.00%2,000,000
TELA BIO INCTELADECR$5,490-0.08%0.72%$15.040.01%365,000
FIBROGEN INCFGENDECR$5,452-0.10%0.71%$37.090.00%147,000
VERASTEM INCVSTMINCR$4,7610.49%0.62%$2.050.06%2,325,000
MEI PHARMA INCMEIPDECR$4,108-0.15%0.54%$2.640.00%1,556,000
KINIKSA PHARMACEUTICALS LTDKNSADECR$3,960-0.55%0.52%$17.67-0.34%224,100
KEZAR LIFE SCIENCES INCKZRINCR$3,6960.13%0.48%$5.220.04%708,000
APTOSE BIOSCIENCES FAPTODECR$3,504-0.68%0.46%$4.38-0.56%800,000
PRAXIS PRECISION MEDICINES IPRAXBUY$3,4890.00%0.46%$55.020.00%63,416
RHYTHM PHARMACEUTICALS INCRYTMBUY$3,4190.00%0.45%$29.730.00%115,000
EDAP TMS S.A.EDAPDECR$3,399-0.29%0.44%$5.17-0.37%657,500
ESSA PHARMA INCEPIXINCR$3,3890.81%0.44%$11.930.05%284,050
CONCERT PHARMACEUTICALS INCCNCEINCR$3,2112.27%0.42%$12.641.54%254,000
CONTRAFECT CORPCFRXBUY$2,2220.00%0.29%$5.050.00%440,000
OPTINOSE INCOPTNBUY$1,8010.00%0.24%$4.140.00%435,000
SIERRA ONCOLOGY INCSRRABUY$1,2080.00%0.16%$16.030.00%75,379
AMARIN CORP PLCAMRNINCR$1,1000.16%0.14%$4.890.00%225,000
FULCRUM THERAPEUTICS INCFULCDECR$1,034-0.71%0.14%$11.71-0.80%88,300
AKOUOS INCAKUSBUY$9010.00%0.12%$19.820.00%45,459
CATALYST BIOSCIENCES INCCBIOBUY$9390.00%0.12%$6.310.00%148,800
CATABASIS PHARMACEUTICALS INCATBBUY$4020.00%0.05%$2.140.00%187,750
MAGENTA THERAPEUTICS INCMGTABUY$3750.00%0.05%$7.840.00%47,804
AVEO PHARMACEUTICALS INCAVEOBUY$3390.00%0.04%$5.770.00%58,800
BIOLINERX LTDBLRXINCR$420.27%0.01%$2.520.00%16,667
AEGLEA BIOTHERAPEUTICS INCAGLESOLD$00.00%-100.00%$0.000.00%0
AVENUE THERAPEUTICS INCATXISOLD$00.00%-100.00%$0.000.00%0
AXOVANT SCIENCES LTDSOLD$00.00%-100.00%$0.000.00%0
CIDARA THERAPEUTICS INCCDTXSOLD$00.00%-100.00%$0.000.00%0
CRINETICS PHARMACEUTICALS INCRNXSOLD$00.00%-100.00%$0.000.00%0
MINERVA NEUROSCIENCES INCNERVSOLD$00.00%-100.00%$0.000.00%0
ONCTERNAL THERAPEUTICS INCONCTSOLD$00.00%-100.00%$0.000.00%0
OUTSET MED INCOMSOLD$00.00%-100.00%$0.000.00%0
PIERIS PHARMACEUTICALS INCPIRSSOLD$00.00%-100.00%$0.000.00%0
X4 PHARMACEUTICALS INCXFORSOLD$00.00%-100.00%$0.000.00%0